Hyaluronic Acid: What It Does and How to Use It
Hyaluronic acid (HA) is a natural molecule your body makes to hold water — in skin, joints, and eyes. You’ve probably seen it listed on serums, dermal fillers, supplements, and knee injections. It’s simple: HA helps hydration and cushioning. But not every product or use works the same way. This page gives clear, practical advice so you know what to expect and how to pick the right option.
Topical vs injected: what to expect
Topical HA (serums, creams) mainly boosts surface hydration. If skin looks plumper or smoother after using a serum, that’s the HA drawing water to the top layer. Look for products that list hyaluronic acid or sodium hyaluronate near the top of the ingredients. Higher concentrations don’t always mean better results — formulation matters (molecular weight, humectants, and the product base).
Injectable HA is used as a filler for wrinkles and to lubricate joints. Dermal fillers add volume and can last months to more than a year depending on the product and area treated. For knee osteoarthritis, clinical trials show HA injections can reduce pain and improve function for several months in some people. Injection results are stronger and longer-lasting than topical treatments, but they carry more risk and should only be done by a licensed practitioner.
Practical tips: choosing and using HA
For skin: use a lightweight serum with HA plus a moisturizer to lock moisture in. Apply on damp skin, then seal with a cream. If you use retinol or vitamin C, HA pairs well — it reduces dryness and irritation. Watch for multi-ingredient products that list alcohol high up; that can dry skin out and cancel benefits.
For fillers and joint injections: pick a certified clinic. Ask about the brand, expected duration, common side effects (swelling, bruising, temporary lumpiness), and the practitioner’s complication plan. After injections, avoid heavy exercise and extreme heat for 24–48 hours. If you see signs of infection or severe pain, contact your provider immediately.
Supplements: some people take oral HA for joint comfort. Typical supplement doses on the market range from about 100–200 mg per day. Results vary; talk with your doctor, especially if you take blood thinners or have a medical condition.
Safety checklist before buying: buy from authorized sellers or pharmacies, check expiration dates, read ingredient lists, and do a patch test for topicals. Pregnant or breastfeeding? Ask your clinician. Allergic reactions are rare but possible.
Want more detail on a specific product or treatment? Browse our guides and reviews for deeper looks at serums, fillers, supplements, and clinics. Knowing the differences and following simple safety steps will help you get the results you want without surprises.